Nor-NOHA monoacetate

CAS No. 2250019-93-1

Nor-NOHA monoacetate( —— )

Catalog No. M35154 CAS No. 2250019-93-1

nor-NOHA monoacetate (Nω-Hydroxy-nor-L-arginine) is a highly potent and selective arginase inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 81 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Nor-NOHA monoacetate
  • Note
    Research use only, not for human use.
  • Brief Description
    nor-NOHA monoacetate (Nω-Hydroxy-nor-L-arginine) is a highly potent and selective arginase inhibitor.
  • Description
    nor-NOHA monoacetate is a selective and reversible arginase inhibitor. nor-NOHA monoacetate induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA monoacetate has anti-leukemic activity. nor-NOHA monoacetate can used in study of endothelial dysfunction, immunosuppression and metabolism.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Arginase
  • Recptor
    Arginase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2250019-93-1
  • Formula Weight
    236.23
  • Molecular Formula
    C7H16N4O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (423.32 mM; Ultrasonic )H2O : 50 mg/mL (211.66 mM; Ultrasonic)
  • SMILES
    CC(O)=O.N[C@@H](CCNC(=N)NO)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ng KP, et al. The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target. PLoS One. 2018 Oct 11;13(10):e0205254.?
molnova catalog
related products
  • Nω-Hydroxy-nor-L-Arg...

    Nω-Hydroxy-nor-L-Arginine Dihydrochloride?is a competitive and reversible inhibitor of arginase.

  • Nor-NOHA monoacetate

    nor-NOHA monoacetate (Nω-Hydroxy-nor-L-arginine) is a highly potent and selective arginase inhibitor.

  • Urea

    A compound formed in the liver from ammonia produced by the deamination of amino acids.